burkitt lymphoma | Burkitt Lymphoma

Burkitt Lymphoma

The DEFINITION of the
Burkitt Lymphoma non-Hodgkin's lymphoma is the high level of the derived from B lymphocytes and tends to spread to areas outside of the lymph system (such as bone marrow, blood, central nervous and fluid composition spinalis).
Burkitt lymphoma can occur at any age, but is most often found in children and young adults, especially men.
The disease can also occur in people with AIDS.

The CAUSE of the
Unlike other Lymphoma, Burkitt lymphoma has spread geographically.
Most often found in Central Africa and is rare in the US. The cause is the Epstein-Barr virus, which causes Mononucleosis infeksiosa on people who live in the U.S.; Burkitt Lymphoma sufferers but cannot transmit the disease to others.
Why the same virus causes Lymphoma in Central Africa, but causes Mononucleosis infeksiosa in the U.S., still unable to understand.

SYMPTOMS
A large number of cells lymphoma can be heaped up in the lymph nodes and organs of the abdomen, causing swelling.
Cell lymphoma can get into the small intestine, causing a blockage or bleeding.

Found swelling of the neck and jaw, sometimes inflicting pain.

DIAGNOSIS
To enforce a diagnosis, biopsy of abnormal tissue and performed a procedure to determine the extent of the spread of the disease (specify stadium).
Sometimes the disease is still limited to a single area (is localized).
If at the time of terdiagnosa lymphoma has already spread to the bone marrow, blood, or central nervous system, then the prognosis is worse.

TREATMENT
Without treatment, Burkitt Lymphoma develops quickly and be fatal.
Probably needed surgery to remove the affected colon area, so that is not the case of bleeding, blockage or rupture.

Chemotherapy given intensively, in the form of a combination of methotrexate, siklofosfamid, vinkristin, doksorubisin and sitarabin.
Chemotherapy can cure about 80% of sufferers the lymphoma is localized and still 70% of sufferers of lymphoma that has been little spread. For disease that has spread widely, figures his recovery reached 50-60%, but drops to 20-40% if lymphoma has invaded the central nervous system or the bone marrow.